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Cidofovir is used to treat conditions of cytomegalovirus retinitis, an infection of the retina of the eye. Cidofovir is also efficient in the treatment of acyclovir-resistant HSV infections. Cidofovir has also been investigated to help in the treatment of progressive multifocal leukoencephalopathy. Since Cidofovir has anti-smallpox efficacy, it can be used in bioterror incidents involving smallpox cases. Cidofovir can as well be used as an antitumor agent. Cytomegalovirus retinitis can be seen in the body with the symptoms such as inflammation of the retina, blindness, itching in the eye, and headache. Cidofovir works by stopping the replication of the DNA responsible for growth of a virus. Below you will find the uses of cidofovir.
- Viral infections
Dosage of Cidofovir depends on the individual and the condition being treated. The dosage for pediatrics under 18 years old has not been established. Adult dosage can be prescribed differently after various conditions of the body put in place. It is advisable to take the prescription as prescribed by the health care provider to minimize other side effects in the body. The typical dosage for Cidofovir is given as follows. CMV Retinitis
- Induced dose: 5 mg/kg once a week for two weeks
- Maintenance: 5 mg/kg once every two weeks
- Smallpox: 5 mg/kg once
- Serum creatinine (SCr): 0.3-0.4 mg/dL above baseline: Reduce to 3 mg/kg IV
Cidofovir Side Effects
Side effects related to Cidofovir are as below; however, before you start using Cidofovir drug, consult your physician about all the expected side effects. If these side effects become bothersome, seek medical attention as soon as possible. The common side effects of Cidofovir include the following. Note that not all possible side effects are listed.
- Decreased appetite
- hair loss
Severe side effects of Cidofovir include:
- dark urine
- eye irritation
- fast heartbeat
- shortness of breath
- unusual bleeding
- vision changes
Different medications can interact with Cidofovir, altering its intended purpose in the body. It is advisable to disclose the list of medication you are using presently or those you are planning to use, those prescribed or over-the-counter, herbal, and vitamin to the doctor. If you find yourself experiencing unusual allergic reactions to Cidofovir, report to the physician immediately for treatment. The correct dosage should be emphasized to avoid future interactions. Some of the drugs that may interact with Cidofovir include the following. Note that not all possible interactions are listed.