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Proleukin contains an active ingredient referred to as aldesleukin. Aldesleukin is the synthetic equivalent of the protein based substance in your body known as Interleukin 2 (IL-2), which influences the response of your body's immune system by directly impacting the differentiation of the T cells. Proleukin manages to slow down or completely halt the multiplication of cancerous cells by mimicking the functions of the interleukins protein and promoting the differentiation and specialization of the T cells.
The active component of Proleukin (aldesleukin) attaches itself to the interleukins 2 receptors which later leads to the activation of the receptor complex which promotes the multiplication and differentiation of the T cells that assist in shrinking and curbing cancerous cells. Proleukin is primarily used to treat the following conditions.
- Malignant skin cancer
- Kidney cancer
- May be utilized in the treatment of Kaposis sarcoma
- Renal cancer
Proleukin is a drug that is utilized in chemotherapy regimens. It is, therefore, mandatory to observe the set dosages unless altered by your doctor after observation. The dose is set based on The patients' response to the drug The severity of the medical condition Any drug contra dictations The doses are as follows
- The set dose for treating an adult with renal carcinoma or malignant skin cancer is 0.037 mg/kg administered intravenously within an 8 hour period via a 15-minute intravenous drip, for a round of 14 doses.
- This treatment round should be followed by a break of about 9 days before resuming another 14 doses observing the same routine.
- Patients suffering from metastatic melanoma have their doses peaked up to 18 doses within the first round of treatment.
Proleukin Side Effects
Like most drugs used during chemotherapy, Proleukin also has some common side effects that may accompany the use of the drug. However, it is important to know that the function of the drug and its purpose far outweighs the side effects you may experience while under treatment.
Some of these common side effects include:
- Lack of appetite
- Dizzy spells
- Muscle rigidity
- Gaining weight
- Mouth sores
Serious side effects:
- Blurred vision
- Darkened urine
- Mental alterations
- Problems breathing
- Irregular cardiac rhythms
- Increased thirst
Drug interactions are vital to monitor because they greatly impact the effectiveness of the drug and can put you at an even greater risk of experiencing adverse side effects. It is important that you openly inform your doctor of any medication you might be taking before the treatment is initiated so that they may rule out any interactions that may impact your treatment course negatively.
Proleukin has been discovered to interact with the following substances: