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Daclizumab is used to prevent organ rejection in kidney transplant. Daclizumab can as well be combined with other medication to treat multiple sclerosis. Daclizumab is employed to slow the progression of autoimmune diseases, particularly that of birdshot chorioretinopathy. Daclizumab is an antibody and immunosuppressive agent that works by blocking the activation of immune system decreasing the risk of transplant rejection. Signs and symptoms of kidney rejections include fluid retention, high temperature over 100 degrees, pain and tenderness around the transplanted kidney, weight gain, and flu-like symptoms. Daclizumab should be used as advised to realize its intended effectiveness.
- Organ Rejection
- Multiple Sclerosis
Daclizumab dosage can be prescribed differently according to the reaction of the body and type of the transplant done. Most doctors will give different regimen; however it is advisable to use the prescription of your doctor. In case, the symptoms of transplant failure persist, seek medical attention as first as possible. The mostly used prescription is given as below. Adult and pediatric dosage are typically the same.
- 1 mg/kg administered via central vein over 15 minutes period.
- The Standard course of therapy includes five doses: the first dose is given 24 hours before transplantation; the remaining four is given at intervals of 14 days.
Daclizumab Side Effects
Several body complications are realized during the treatment with Daclizumab. In case the listed side effects persist, seek medical attention with an immediate effect. The dosage should be taken as advised to minimize instances of severe side effects
- back pain
- fluctuation in blood pressure
- leg cramps
- muscle pain
- night sweats
- stomach pain
Severe side effects of Daclizumab include:
- severe allergic reactions
- difficulty breathing
- tightness in the chest
- abnormal heartbeat
- chest pain
Daclizumab drug interaction decreases its intended purpose in the body. Before Daclizumab is given, ensure to disclose all the list of medication you are using for a better regimen. Use the correct dosage as given by the healthcare professional. If you are allergic to Daclizumab, tell your doctor at once. Some of the medications proven to cause interaction with Daclizumab include: