Erythropoiesis-Stimulating Agents

Erythropoiesis Stimulating Agents, also as known as ESAs, are prescription drugs similar to the naturally produced erythropoietin (EPO). EPO is a hormone produced by healthy kidneys and that stimulates the bone marrow to produce red blood cells. There are some conditions that limit the production of the EPO hormone such as chronic kidney failure or chemotherapy. ESA is administered at this point to the persons with such complications. It is also administered to reduce the frequency of blood transfusions before and after major surgeries.


Erythropoiesis-Stimulating Agents Drugs

Drugs classified as Erythropoiesis-Stimulating Agents include the following.

  • Epoetin Alfa (Epogen)
  • Epoetin Beta (Neorecormon)
  • Darbepoetin Alfa (Aranesp)
  • Methoxy polyethylene glycol-epoetin beta (Mircera)


Erythropoiesis-Stimulating Agents Uses

ESAs are usually administered to treat anaemia, a side effect of other conditions. Below you will find a list of some of the conditions ESAs are used to treat.

  • Chronic Kidney Failure
  • Premature Babies
  • Cancer
  • Hemodialysis


Erythropoiesis-Stimulating Agents Side Effects

Side effects for patients of this drug include

  • Dizziness
  • Nausea
  • High Blood Pressure
  • Skin rash
  • Pain at the injected area
  • Blood clots

Consult your doctor immediately if you experience the following side effects:

  • Numbness in the face, arms or legs
  • Shortness of breath and chest pains


Erythropoiesis-Stimulating Agents Interactions

Like with any other prescription drug, it is important that you consult a qualified medical professional before taking ESA as it may not interact well with other drugs and medications. Avoid alcohol, fatty and oily foods because ESA is known to increase the risk of high blood pressure and blood clotting.

Main Erythropoiesis-Stimulating Agents Drugs

Procrit Epogen Aranesp


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