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Patients who have irregular heartbeats and high blood pressure caused by surgery may be prescribed esmolol to manage these conditions. Esmolol may be used to treat high blood pressure and fast heartbeat during and after surgery. It affects how certain parts of the body such as the heart response to nerve impulses. Esmolol allows the heart to beat slower and reduces blood pressure. Lowering blood pressure increases the amount of blood and oxygen to the heart. Esmolol may also be used when aortic dissection is suspected in a patient. In aortic dissection, there is tearing in the inner wall of the aorta, which allows blood to flow in between layers of the walls making them force apart.
- Irregular Heartbeats
- High Blood Pressure
Esmolol is administered by slow intravenous injection. It is usually administered in clinical settings where a doctor can monitor vital signs such as heart rates and blood pressure, and where emergency situations could be handled adequately. The dosage may depend on the condition being treated and the response to treatment.
- For adequate control of hypertension, higher dosages of 250 to 300 mcg/kg/min may be required.
- For treatment of atrial fibrillation and atrial flutter, or supraventricular tachycardia, a loading infusion of 0.5 mg/kg/minute is given over one minute and a maintenance dose of 0.05 mg/kg/min for about 4 minute
- For treatment of intra or postoperative supraventricular tachycardia or hypertension, a 1 mg/kg bolus dose is given over 30 seconds then followed by a 150 mcg/kg/minute dose
Esmolol Side Effects
Patients administered esmolol may develop side effects. Some may have minor side effects while others could develop serious effects. If common side effects last for long or they become intolerable, check with a doctor. Signs of allergic reaction and other severe side effects require one to seek medical attention right away. Common side effects likely to develop are;
Severe side effects that could develop are;
- Tightness in chest
- Difficult breathing
- Swelling of body parts like tongue and throat
- Unusual hoarseness
- Chest, arm, or jaw pain
- Mental changes
- Unusual sweating
- Severe nausea
- Shortness of breath
Taking other drugs along with esmolol may cause drug interaction resulting in serious side effects or decreased effectiveness of the medicines. The list below shows drugs that could interact with esmolol. However, it may not be complete. Other medicines and substances not listed here could interact with esmolol. Tell your doctor if you have other medicines you have been prescribed or purchased over the counter before you are administered esmolol.