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Granocyte 34 Injection Vials Uses
Granocyte 34 injection vials are used to increase the amount of white blood cells. Granocyte injection contains lenograstim, which is a type of drug that stimulates the bone marrow to produce white blood cells referred to as neutrophils. Neutrophils are naturally produced by the bone marrow and play a major role in the body's immune system because they help in defending the body from infections. Low levels of neutrophils leave a person vulnerable to life-threatening conditions. Neutropenia can be caused by several factors, cancer chemotherapy being one of them. Peoples white blood cells recover faster after chemotherapy, but with some kinds of chemotherapy, like high-dose treatment, it can take a longer time for white blood cells to return to their previous count. Granocyte triggers the bone marrow to produce neutrophils. Granocyte corrects low neutrophil levels in the blood and reduces the severity and duration of neutropenia. Therefore, Granocyte eliminates the need for antibiotic treatment.
- White Blood Cell Deficiency
Granocyte 34 Injection Vials Dosage
Granocyte needs to be administered at an experienced oncology or hematology center. Granocyte can be given by intravenous infusion or by sub-cutaneous injection. Each vial of Grancocyte should with dissolved with 0.1mL sterile water.
- The recommended Granocyte dose is 19.2 MIU (150 micrograms) per meter squared per day, therapeutically equivalent to 0.64 MIU/kg per day for: Established cytotoxic chemotherapy, Bone marrow or peripheral stem cells transplantation, and PBPC mobilization after chemotherapy.
- The recommended dose is 1.28 MIU per kg/day for PBPC mobilization with Granocyte alone
- In case, one is having a stem cell transplant or bone marrow transplant. Usually, one course of Granocyte is recommended
- In case, one is a healthy donor of stem cells, only a single course of Granocyte is recommended ( with 28 consecutive days of treatment as maximum)
- In case one is having chemotherapy, the doctor may prescribe a number of courses of treatment with Granocyte
- In case one has congenital neutropenia, the doctor may prescribe intermittent or continuous treatment with Granocyte.
Granocyte 34 Injection Vials Side Effects
Granocyte can cause some side effects and should be used with great caution. Patients should be wary of side effects that become persistent or worsen. Common Granocyte side effects
- Headache, fever, feeling sick, pain in the bones and back
- Feeling tired, easy bruising or bleeding
- Temporary alterations in blood tests
- A reaction at the injection site
Rare Granocyte side effects
- Pain in the upper left side of the stomach or left shoulder
- Allergic reaction
- Serious allergic reaction referred to as anaphylactic shock' (includes difficulty breathing or swelling of the face, feeling faint, and weakness)
- Experiencing a breathing problem (cough, fever, feeling out of breath)
- Skin problems like plum colored, raised areas on the patient's legs or arms and sometimes on the neck, or face with fever (indicating sweets syndrome')
- Raised red lumps with headache and fever (indicating Lyells' syndrome)
- Other skin problems like red erect bruises on the legs or ulcers on the patient's body, with joint pain and fever
Granocyte 34 Injection Vials Interactions
Drug interactions can change how Granocyte works or increase the risk of serious side effects. Patients should inform their doctors about the use of other medications before and after the use of Granocyte to enable doctors evaluate those drugs for any possible interaction. Using Granocyte is prohibited during the 24 hour period following or preceding chemotherapy due to the sensitivity of quickly dividing myeloid cells to cytotoxic chemotherapy.
- Granocyte is not known to interact with other medications. However, it is important for a patient to inform their doctor about the use of any new medication.