Hyaluronate is a drug that is synthesised from hyaluronic acid. This is a naturally occurring substance that is normally found in various nervous, epithelial and connective tissues. Hyaluronate is a non-sulfated glycosaminoglycan, which makes it different from the other glycosaminoglycans. Hyaluronate is marketed under trade names like Euflexxa and Hyalgan. Hyaluronate is normally used to treat knee pain in patients who are suffering from osteoarthritis, this is because it acts as a shock absorber and a lubricant.