Irbesartan is an angiotensin receptor blocker that works by relaxing tension in the blood vessels. It is used to treat hypertension (high blood pressure) and also as a remedy to kidney problems brought on by diabetes (diabetic nephropathy). As with all drugs, before taking this medication, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. You should also let your doctor know if you are pregnant or breastfeeding, and if you have any allergies to drugs or foods.This drug is often prescribed in combination with a change in diet or exercise regime. You should be certain to make these changes as your doctor instructs.