Methotrexate Coupon and Discount

Our Methotrexate coupon and discount will save you up to 75%* off your prescription. Methotrexate is a prescription drug that treats cancer, autoimmune diseases, severe psoriasis, rheumatoid arthritis and ectopic pregnancy. The original cash price of Methotrexate is not available. If your insurance does not cover this cost, use our Methotrexate coupon to reduce the price. Choose if you would like to receive your Rebates prescription coupon by mail, email, text, or print. Continue reading below for more information on Methotrexate.
Methotrexate Overview
Drug Name: Methotrexate Brand Name(s): Rheumatrex Dose Pack, Trexall Drug Class: Antimetabolite Treats: Cancer, Autoimmune Diseases, Severe Psoriasis, Rheumatoid Arthritis, Ectopic Pregnancy
Methotrexate is an antifolate and antimetabolite drug which treats certain diseases associated with rapid growth of cells, e.g. cancer cells, skin cells, bone marrow cells, placenta cells. Methotrexate may be administered orally in the form of tablets or in the form of injection (intravenous, intramuscular, subcutaneous, or intrathecal).
  • Methotrexate Discount Coupon - Save Up To 75%* Off!

    The free Rebates.com Methotrexate Coupon and Discount Card can save you up to 75%* off your prescription prices. All you have to do is print the coupon and bring it to the pharmacy to receive the benefits of our drug discount program. This coupon is not insurance and is not valid in combination with any government-sponsored drug plans.
    Methotrexate Coupon
    Average Savings:
    75%* Off
    How to use your Methotrexate Coupon:
    1. Click the "Get Coupon" button below and choose to receive your Methotrexate coupon by Print, Email, or Text Message.
    2. Bring your discount coupon to the pharmacy and show it to your pharmacist when you fill your prescription.
    3. Save up to 75%* off your prescription!
  • Methotrexate Uses

    Methotrexate is used to treat cancer, inflammatory skin diseases, arthritis, and ectopic pregnancy. While treating cancer higher doses of Methotrexate are used. Methotrexate can cause serious side effects; therefore, it is used after unsuccessful treatment with other medicines or in cases where the disease cannot be treated with other medications. Below you will find more precise list of conditions that are treated by using Methotrexate:
    • Cancer, such as breast cancer, skin cancer, leukemia
    • Psoriasis
    • Psoriatic arthritis
    • Rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, polymyositis
    • Ectopic pregnancy
  • Methotrexate Dosage

    Methotrexate is a prescribed drug and the dosage strictly depends on the individual condition of a patient, the age, and the type of treatment. Methotrexate is administered orally or by injection in 15 to 30 mg doses daily for the course of 5 days. In most cases, 3 to 5 courses are required, with rest periods of one week or more. Sometimes Methotrexate is taken weekly to lower its toxicity.

    Dose for Acute Lymphoblastic Leukemia:

    • Induction: tablets, 3.3 mg/m2/day or IM, 60 mg/m2 in combination with prednisone
    • Maintenance: IM,15 mg/m2 or tablets twice a week
    • Alternate remission dosing: 2.5 mg/kg IV, every 14 days

    Dose for Lymphoma:

    • Burkitt's tumor in Stages I-II: 10, 25 mg orally daily (4 to 8 days)
    • Malignant lymphoma in Stage III: 0.625, 2.5 mg/kg orally daily

    Other doses

    • Dose for Choriocarcinoma / Trophoblastic Disease: IM, 15 to 30 mg or orally daily for five days
    • Dose for Meningeal Leukemia: 12 mg/m2 intrathecally every 2, 5 days until the cell count of the CSF returns to normal
    • Dose for Mycosis Fungoides: 25 mg IM twice a week or 50 mg IM once a week or 2.5, 10 mg PO daily
    • Dose for Osteosarcoma: Initial Dose: 12 g/m2 intravenously as a 4-hour infusion
    • Dose for Psoriasis: single dose (10, 25 mg/week orally, IM, or IV) or divided dose (3 doses, 2.5 mg orally, IM, or IV every 12 hours/week)
    • Dose for Rheumatoid Arthritis: single dose (7.5 mg orally weekly) or divided dose (3 doses, 2.5 mg orally every 12 hours/week)
    • Dose for Neoplastic Diseases: I.V. from 30-40 mg/m2/week to 100-12,000 mg/m2 with leucovorin rescue
  • Methotrexate Side Effects

    Methotrexate may cause life-threatening or serious side effects related to high toxicity of the bone marrow, kidneys, lungs, or liver. You should constantly monitor your health during high-dose treatment with Methotrexate. The most common side effects from taking Methotrexate may be related to:
    • Liver problems - clay-colored stools, nausea, itching, tired feeling, upper stomach pain, loss of appetite, jaundice, or dark urine
    • Severe skin reaction - burning in eyes, swelling of face or tongue, sore throat, fever, skin pain with purple rash
    Other side effects from Methotrexate:
    • Shortness of breath, dry cough
    • Vomiting, diarrhea, upset stomach
    • Blurred vision
    • Dizziness, headache, or tired feeling
    • Easy bruising, pale skin, weakness, unusual bleeding
    • Rapid weight gain, swelling, little or no urinating
    • Seizure
    However, some of the side effects may need no medical attention as they may disappear during treatment.
  • Methotrexate Interactions

    Methotrexate may have interactions with drugs, diseases, food, and alcohol. Taking other medications with Methotrexate may increase the risk for side effects. Methotrexate may interact with 758 drugs, particularly: Food/Alcohol interactions with Methotrexate:
    • Caffeine, reduces the arthritis treatment effectiveness
    • Alcohol, can cause problems with liver
    Disease Interactions with Methotrexate:
    • Liver disease
    • Kidney disease
    • Lung disease
    • Blood cell disorder
    • Bone marrow disorder
    • Stomach ulcers
    • Infections
    • Pregnancy or breast-feeding
    • Radiation treatment