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Methoxsalen is used to help control skin disorders such as vitiligo. It may also be used to treat psoriasis and cutaneous T-cell lymphoma-CTCL. For treating psoriasis, the combination helps slow the overgrowth of skin cells, where with the treatment of vitiligo, the combination helps increase the number of melanocytes (pigment-producing cells in the skin.
- Skin Disorders
Individual dosage will be determined by your healthcare provider for each patient case because Methoxsalen dosage strength is based on your weight, medical condition and response to treatment. The amount of UV exposure for each treatment is based on skin type and response to treatment. It is possible to have UVA treatment 2 to 4 times a week initially then tapered off as your condition improves. Take Methoxsalen by mouth with food or milk 2 to 4 hours prior to UV light treatment or as directed by your physician. Wear wrap-around sunglasses to block out UVA light for 24 hours after taking the capsule to prevent UVA rays from entering the eyes.
Methoxsalen Side Effects
As with any medication, you may experience adverse reactions along with the desired results while taking methoxsalen. Some side effects that may occur are nausea or trouble sleeping. When Methoxsalen is used along with UVA light treatment, mild itching, drying, darkening or reddening of the skin may occur. Tell your doctor immediately if you experience any of these unlikely but serious side effects:
- Severe skin reddening
- Burning of the skin
- Thinning or wrinkling skin
- Painful browning, yellowing or whitening of the nails
- Changes in mood (Depression, nervousness)
Some rare side effects may include unusual moles, sores or growths on the skin or blurred vision. This is not a complete list of side effects and you should contact your doctor if you experience any
Like any drug, methoxsalen may interact with other drugs and substances. Some drugs or outside factors may affect the way this medication works or increase the risk of side effects. Make sure you have a list of all medications, herbal supplements, vitamins or minerals you are currently taking to share with your doctor. Some medications that may cause interactions with Methoxsalen are listed below. Note that not all possible interactions are listed.
- Sulfa antibiotics
- Thiazide diuretics
- Tetracycline antibiotics
- Any medication that may affect the sensitivity to light (anthralin, coal tar, phenothiazine)
Do not stop, start or change the dosage of this or other medications without first consulting with your doctor.