The medicine Mipomersen is an antisense therapeutic drug. Mipomersen is a second-generation drug that targets apolipoprotein B. This drug is rapidly and extensively absorbed after subcutaneous administration with a half-life of about 30 days. Mipomersen was previously known as Kynamro and is a generic drug. It is generally a lipid-lowering agent that works by reducing a protein that delivers cholesterol in the blood.