Sinemet is used to treat Parkinson's Disease. The generic version is called Carbidopa and levodopa. The average Sinemet cash price is about $36.47 for a supply of Tablet 25-100 MG 30 pcs. You can reduce your Sinemet cost by up to 75% with our free Sinemet discount card. Bring it to a participating pharmacy near you to save on your prescription medication.