Valtrex is used to treat Chickenpox, Shingles, Herpes simplex. The generic version is called Valacyclovir hydrochloride. The average Valtrex cash price is about $428.42 for a supply of Tablet 1 GM 30 pcs. You can reduce your Valtrex cost by up to 75% with our free Valtrex discount card. Bring it to a participating pharmacy near you to save on your prescription medication.